【双语病例】中枢神经细胞瘤1例MR影像表现

Key Facts

Imaging Findings：

* Best diagnostic clue: ”Bubbly” mass in frontal horn or body of lateral ventricle

* Intraventricular mass attached to septum pellucidum

* Circumscribed, lobulated mass with intratumoral “cysts”

* Ca common, 50%-70%

Top Differential Diagnoses：

* Subependymoma

* Subependymal giant cell astrocytoma (SGCA)

* Metastasis

* Ependymoma

* Choroid plexus papilloma (CCP)

* Meningioma

* Cavernous malformation

Pathology：

* <1% of all primary intracranial neoplasms * Represents 50% of intraventricular tumors in patients 20-40 years * WHO grade Ⅱ

Clinical Issues：

* Most common sign/symptoms: Headache, increased intracranial pressure, mental status changes, seizure

* Hydrocephalus secondary to foramen of Monro obstruction

* Complete surgical resection is treatment of choice

中

中枢神经细胞瘤

要点

影像学表现：

* 诊断要点：侧脑室前角或体部的“多泡沫样”占位

* 附着于透明隔的脑室内占位

* 伴有瘤内囊变、界限清楚、分叶状肿物

* 钙化常见，占50%-70%

主要鉴别诊断：

* 室管膜下瘤

* 室管膜下巨细胞星形细胞瘤

* 转移瘤

* 室管膜瘤

* 脉络丛乳头状瘤

* 脑膜瘤

* 海绵状血管畸形

病理学：

* 占所有颅内原发肿瘤比例<1% * 20-40岁脑室内肿瘤的患者中50%为本病 * 类似于少突胶质细胞瘤 * WHO Ⅱ级

临床表现：

* 最常见的症状/体征：头痛、颅内压增高、精神状态改变、癫痫发作

* 室间孔梗阻导致继发性脑积水

* 治疗的最佳方案是手术切除